In this paper, we propose a mathematical model that combines chemotherapy and oncolytic virotherapy as an alternative to treatment of a glioma. The main idea is to incorporate the virotherapy… Click to show full abstract
In this paper, we propose a mathematical model that combines chemotherapy and oncolytic virotherapy as an alternative to treatment of a glioma. The main idea is to incorporate the virotherapy after the first or second chemotherapy session using a specialist virus that attacks only tumor cells. Some simulations are presented. Based on the results, we conclude that with this combined therapy may reduce the number of chemotherapy sessions and may lead to obtain better results in the fight against gliomas.
               
Click one of the above tabs to view related content.