LAUSR

Porphyrins and 68Ga have emerged as novel synergic options for PET applications so the idea of preparation of a novel porphyrin complex using this nuclide was targeted. Herein, [68Ga(III)] labeled 5, 10, 15, 20-Tetrakis(2, 4, 6-trimethoxy phenyl) porphyrin ([68Ga(III)]-TTMPP) was developed in this work. The biodistribution of the [68Ga(III)]-TTMPP complex among vital organs of mice bearing Fibrosarcoma tumors was studied using scarification. Due to the short half-life of 68Ga, high tumor avidity and fast excretion of [68Ga(III)]-TTMPP complex, this labeled compound is demonstrated to be a potential bioprobe for positron emission tomography (PET) and photodynamic therapy (PDT).