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Neutron activation analysis for determination of metal ions in biological fluids of patients after CoCrMo arthroplasty

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Determination of metals and trace elements in patients with total knee or hip arthroplasty with CoCrMo alloy was performed. Blood, urine and cerebrospinal fluid (CSF) samples were analyzed and compared… Click to show full abstract

Determination of metals and trace elements in patients with total knee or hip arthroplasty with CoCrMo alloy was performed. Blood, urine and cerebrospinal fluid (CSF) samples were analyzed and compared with samples from healthy people. Levels of Co, Cr as well as Na, Ca, Fe, Zn, Se, Rb, Sb and Br were determined by means of neutron activation analysis. The values of Cr and Co of the blood and urine measurements were elevated in patients with replacement, and according to the statistical analysis, significant differences of the elements Zn, Br, Co and Sb were found in the CSF (pā€‰<ā€‰0.05).

Keywords: analysis; activation analysis; neutron activation; analysis determination

Journal Title: Journal of Radioanalytical and Nuclear Chemistry
Year Published: 2019

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