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Synthesis of some new triamide derivatives via Ugi five-component reaction in aqueous solution

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AbstractTriamide derivatives have been synthesized in good yields in a novel, one-pot, five-component, and efficient process by the reaction of Z-oxazolone, water, primary amines, aldehydes, isocyanides, in the presence of… Click to show full abstract

AbstractTriamide derivatives have been synthesized in good yields in a novel, one-pot, five-component, and efficient process by the reaction of Z-oxazolone, water, primary amines, aldehydes, isocyanides, in the presence of catalytic amount of KAl(SO4)2ยท12H2O (alum) as a non-toxic, reusable, inexpensive, and easily available reagent via Ugi reaction in aqueous solution.

Keywords: reaction aqueous; five component; via ugi; reaction; aqueous solution

Journal Title: Molecular Diversity
Year Published: 2018

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