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Synthesis and crystal structures of phenylalanine ester-introduced palladium(II) and platinum(II) complexes and their cytotoxicities

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Abstract Phenylalanine ester-introduced palladium(II) and platinum(II) complexes were synthesized. Taking advantage of the formation of Schiff bases by amino acids as an intermediate, the pyridylimine moiety coordinated to a metal… Click to show full abstract

Abstract Phenylalanine ester-introduced palladium(II) and platinum(II) complexes were synthesized. Taking advantage of the formation of Schiff bases by amino acids as an intermediate, the pyridylimine moiety coordinated to a metal center. Single crystals of each complex were obtained successfully, and their molecular structures were clarified in detail. The Pd(II) complex showed remarkable cytotoxicity compared to the Pt(II) complex.

Keywords: ester introduced; palladium platinum; introduced palladium; phenylalanine ester; platinum complexes

Journal Title: Research on Chemical Intermediates
Year Published: 2018

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