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Effects of some 5-anilino-1,2,4-thiadiazole derivatives onto leukemic cells

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The antileukemic activities of some thiadiazole derivatives in the forms of hydrochlorides and salicylates have been determined. The insertion of salicylate ion in the compound increases the therapeutic index, mainly… Click to show full abstract

The antileukemic activities of some thiadiazole derivatives in the forms of hydrochlorides and salicylates have been determined. The insertion of salicylate ion in the compound increases the therapeutic index, mainly due to the reduction of cytotoxicity against healthy cells.

Keywords: derivatives onto; leukemic cells; effects anilino; anilino thiadiazole; onto leukemic; thiadiazole derivatives

Journal Title: Russian Chemical Bulletin
Year Published: 2017

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