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New 1,3-dihydroxyacridine-9-carboxylic acids were obtained by Pfitzinger reaction from 2,4,6-trihydroxytoluene (methylphloroglucinol). Their bromination and azo-coupling reactions were studied. Computer simulation was used to determine potential pharmacokinetic and toxic properties of… Click to show full abstract
New 1,3-dihydroxyacridine-9-carboxylic acids were obtained by Pfitzinger reaction from 2,4,6-trihydroxytoluene (methylphloroglucinol). Their bromination and azo-coupling reactions were studied. Computer simulation was used to determine potential pharmacokinetic and toxic properties of the synthesized compounds.
Keywords:
synthesis new;
acridine carboxylic;
carboxylic acid;
acid derivatives;
new acridine
Journal Title: Russian Chemical Bulletin
Year Published: 2018
Link to full text (if available)
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Journal Title: Russian Chemical Bulletin
Year Published: 2018
Link to full text (if available)
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recommendations!