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A new original approach to the design of anticancer drugs based on energy-rich quadricyclanes

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Quadricyclane derivatives are shown for the first time to be promising for application as anticancer drugs. The efficiency of such cage compounds is mainly due to thermal action on cancer… Click to show full abstract

Quadricyclane derivatives are shown for the first time to be promising for application as anticancer drugs. The efficiency of such cage compounds is mainly due to thermal action on cancer cells resulting from a C—C bond cleavage in quadricyclane on exposure to catalytic amounts of cisplatin Pt ions.

Keywords: new original; original approach; anticancer drugs; approach design; design anticancer; anticancer

Journal Title: Russian Chemical Bulletin
Year Published: 2019

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