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Alkyl perchlorates in the Ritter-type reaction. Synthesis of N-alkylamides

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The Ritter-type reaction of alkyl perchlorates with nitriles of various structures was systematically studied. The reaction has a wide scope and proceeds under extremely mild conditions without any catalysts or… Click to show full abstract

The Ritter-type reaction of alkyl perchlorates with nitriles of various structures was systematically studied. The reaction has a wide scope and proceeds under extremely mild conditions without any catalysts or special activation of reagents. A structural diversity of the obtained by the Ritter-type reaction N-alkyl amides bearing small ring, double bonds, additional functional groups, aromatic and adamantane fragments, was demonstrated.

Keywords: reaction synthesis; ritter type; reaction; perchlorates ritter; alkyl perchlorates; type reaction

Journal Title: Russian Chemical Bulletin
Year Published: 2020

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