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Meta-analysis on big data of bioactive compounds from mangrove ecosystem to treat neurodegenerative disease

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The mangrove ecosystem is one of the wealthiest organic and salt containing ecosystem. It has a large biomass consisting of bacteria, fungi, plants and other potential organisms. The recent boom… Click to show full abstract

The mangrove ecosystem is one of the wealthiest organic and salt containing ecosystem. It has a large biomass consisting of bacteria, fungi, plants and other potential organisms. The recent boom in the discovery of bioactive compounds from the mangrove ecosystem is a potential minefield to inspect for potential drug molecules for various diseases. Meta-analysis offers potential to reveal intrinsic observations from large-scale data. The data that obtained from literature meta-analysis decode the high-throughput results that were mapped. Focusing on the usage of a more stringent method of meta-analysis to elucidate the bioactive compounds from the mangrove ecosystem a total of 365 research articles were analysed here and promised potent drug molecules to isolate from mangrove environment. Meta-analysis was carried using software BibExcel and R program. A total of eight research articles exclusively focused on bioactive compounds as a drug candidate to treat neurodegenerative disease. This article will construct a holistic approach to analyze and explore the vast field of bioactive compounds in the mangrove ecosystem. A systematic review by bibliometric analysis is a streamline method to find out lead molecules as a therapeutic drug molecule to multiple diseases, out of which this review attempts to cover the neurodegenerative diseases. Thus, BibExcel and R program can be implemented in any research field to examine the structure and development undertaken to date.

Keywords: mangrove ecosystem; analysis; bioactive compounds; compounds mangrove; meta analysis

Journal Title: Scientometrics
Year Published: 2020

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