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Prothrombinase: the paradigm for membrane bound enzyme complexes; a memoir

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This review is a brief summary of the history of the development of the Prothrombinase complex paradigm and its incorporation into the “extrinsic pathway”. It summarizes my laboratory’s research from… Click to show full abstract

This review is a brief summary of the history of the development of the Prothrombinase complex paradigm and its incorporation into the “extrinsic pathway”. It summarizes my laboratory’s research from 1968 to 2012 and identifies many of the key players in these efforts.

Keywords: paradigm; paradigm membrane; membrane bound; bound enzyme; prothrombinase paradigm; prothrombinase

Journal Title: Journal of Thrombosis and Thrombolysis
Year Published: 2021

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