LAUSR

The contamination level of 12 antibiotics in 8 species of fish and shrimp from the Dongting Lake, China, was firstly studied. In total, the concentrations of antibiotics in fish and shrimp were lower, which were far lower than the maximum residue limits. The most abundant compound was enrofloxacin followed by sulfadiazine, sulfamethoxazole, sarafloxacin, and sulfadimidine with the highest content from 0.37 to 1.06 ng g−1. The concentrations in Silurus asotus, Cyprinus carpio, and Palinuridae were higher. Concentrations in fish and shrimp from different water layers showed spatial difference, with the order of benthos and middle-lower species > middle-upper species. In addition, the antibiotic content could be affected by the diet, which showed the concentration level of antibiotics decreased in the order of carnivorous > omnivorous > phytophagous species. Human health risk assessment based on potential fish consumption indicates that main antibiotic risk factors were enrofloxacin and sarafloxacin, and main risk species were Silurus asotus and Palinuridae. The daily risk quotient of these antibiotics to rural residents was lower than townsmen. This study is the first report of antibiotic content in fish and shrimp from the Dongting Lake, which could enrich the research of emerging pollutants in aquatic products.