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A novel coumarin-based water-soluble fluorescent probe for endogenously generated SO2 in living cells

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A novel coumarin-based “turn-on” fluorescent probe SS-1 was developed for selective detection of SO2 derivatives in 100% water solution among reactive sulfur species (RSS). The detection limit of the method… Click to show full abstract

A novel coumarin-based “turn-on” fluorescent probe SS-1 was developed for selective detection of SO2 derivatives in 100% water solution among reactive sulfur species (RSS). The detection limit of the method was 91.7 nM. Moreover, the probe exhibited low cytotoxicity and was successfully applied in the imaging of endogenously generated SO2 in HeLa cells.

Keywords: fluorescent probe; novel coumarin; coumarin based; generated so2; endogenously generated

Journal Title: Science China Chemistry
Year Published: 2017

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