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Threshold Dynamics in a Model for Zika Virus Disease with Seasonality

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We present a compartmental population model for the spread of Zika virus disease including sexual and vectorial transmission as well as asymptomatic carriers. We apply a non-autonomous model with time-dependent… Click to show full abstract

We present a compartmental population model for the spread of Zika virus disease including sexual and vectorial transmission as well as asymptomatic carriers. We apply a non-autonomous model with time-dependent mosquito birth, death and biting rates to integrate the impact of the periodicity of weather on the spread of Zika. We define the basic reproduction number \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\mathscr {R}}_{0}$$\end{document}R0 as the spectral radius of a linear integral operator and show that the global dynamics is determined by this threshold parameter: If \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\mathscr {R}}_0 < 1,$$\end{document}R0<1, then the disease-free periodic solution is globally asymptotically stable, while if \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\mathscr {R}}_0 > 1,$$\end{document}R0>1, then the disease persists. We show numerical examples to study what kind of parameter changes might lead to a periodic recurrence of Zika.

Keywords: virus disease; usepackage; disease; document; documentclass 12pt; zika virus

Journal Title: Bulletin of Mathematical Biology
Year Published: 2021

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