The peritoneum is a common site for metastasis from various gastrointestinal tumors. Approximately 7% of colorectal cancers (CRC) present with peritoneal metastases (PM), and up to 19% of CRC develop… Click to show full abstract
The peritoneum is a common site for metastasis from various gastrointestinal tumors. Approximately 7% of colorectal cancers (CRC) present with peritoneal metastases (PM), and up to 19% of CRC develop PM, even after curative surgery.1,2 Furthermore, recurrence is quite common for patients with PM, after cytoreductive surgery, with or without hyperthermic intraperitoneal chemotherapy (CRS ± HIPEC). As demonstrated in a recent study, the deep epigastric lymph node (DELN), at the level of the inferior epigastric artery, may represent a possible dissemination pathway for PMCRC, from the peritoneum to the extraperitoneal compartment.3 The objective of our study was to evaluate the lymphatic pattern of recurrence, focusing on the previously overlooked DELN, in PMCRC patients treated with CRS. Patients and Methods
               
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