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Adenocarcinoma Arising in a Gastric Duplication Cyst

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A 46-year-old female presented to us from her primary care physician with complaints of reflux, dysphagia, crampy abdominal pain, and night sweats. The patient underwent ultrasonography which showed two round… Click to show full abstract

A 46-year-old female presented to us from her primary care physician with complaints of reflux, dysphagia, crampy abdominal pain, and night sweats. The patient underwent ultrasonography which showed two round masses in the upper abdomen. A follow-up CT scan with contrast revealed an 8.2-cm cystic lesion that appeared to be arising from the wall of the stomach, likely representing a gastrointestinal duplication cyst (Fig. 1). On EDG, the patient was found to have an intramural lesion in the greater curvature of the stomach which appeared to originate from the muscularis propria; biopsy from the gastric antrum was negative from intestinal metaplasia, dysplasia, or malignancy. As the patient continued to be symptomatic and there were no contraindications to surgery, an exploratory laparotomy was performed, and the cyst was removed with a partial gastrectomy as it was strongly adhered to the stomach. The pathology report was concerning for moderately differentiated adenocarcinoma arising from a duplication cyst (Fig. 2). The areas of dysplasia and carcinoma positively expressed CK7 and CDX2.

Keywords: cyst; gastric duplication; duplication cyst; arising gastric; adenocarcinoma arising

Journal Title: Journal of Gastrointestinal Surgery
Year Published: 2022

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