LAUSR

Obesity was declared a global health epidemic in 2003 by the World Health Organization. Control of eating in the human brain is provided by several neural systems. Decision-making and cognitive control (prefrontal cortex, cingulate), food and reward expectancy (orbitofrontal cortex, striatum, insula), motor and sensory processing (insula precentral gyrus), learning, emotion and memory (hippocampus, amygdala, striatum), available energy detection, and homeostatic control (hypothalamus, brainstem) may be responsible for an eating behavior. The hypothalamic neurons modulated by anorexigenic and orexigenic hormonal signals (leptin, ghrelin, insülin, amylin, adiponectin, irisin, glucagon-like peptide-1) alter appetite [1–3]. A stroke patient with gradual weight loss is reported.