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The title compound, a key intermediate for preparing Coenzyme Qn family, was prepared in an excellent yield by a reaction sequence starting from the commercially available 3,4,5-trimethoxytoluene 1 via bromination,… Click to show full abstract
The title compound, a key intermediate for preparing Coenzyme Qn family, was prepared in an excellent yield by a reaction sequence starting from the commercially available 3,4,5-trimethoxytoluene 1 via bromination, methoxylation and oxidation reactions. An 80% overall yield was demonstrated on a multi-gram scale.
Keywords:
preparing coenzyme;
efficient synthesis;
key intermediate;
intermediate preparing;
synthesis bromo
Journal Title: Chemical Papers
Year Published: 2019
Link to full text (if available)
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Journal Title: Chemical Papers
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!