LAUSR

ObjectiveTo observe the clinical efficacy of auricular point pricking-bloodletting plus auricular point sticking therapy for acne vulgaris.MethodsA total of 66 patients with acne vulgaris were randomized into an observation group and a control group by the random number table, with 33 cases in each group. The observation group was treated with auricular point pricking-bloodletting plus auricular point sticking therapy, and the control group was treated only with auricular point sticking therapy. The treatments of both groups were performed twice a week, 4 weeks as a course of treatment, for 3 courses in total. The scores of skin lesions and dermatology life quality index (DLQI) scores were recorded before and after treatment to assess the clinical efficacy.ResultsDuring the trial, there were 3 cases of drop-out both in the observation group and the control group. After 3 courses of treatment, the total effective rate of the observation group was 96.7%, while that of the control group was 76.7%. The difference between the two groups was statistically significant (P<0.05). The intra-group comparison showed that the scores of skin lesion and DLQI were both decreased with the increase of treatment times, that was, the scores were lower than those at the previous time point (all P<0.05). After 1, 2, and 3 courses of treatment, the scores of skin lesion and DLQI of both groups were statistically different from those of the same group before treatment (all P<0.05). At every time point during the treatment, the scores of skin lesion and DLQI of the observation group were lower than those of the control group, and the differences between the two groups were statistically significant (all P<0.05).ConclusionAuricular point pricking-bloodletting plus auricular point sticking has a better curative effect than auricular point sticking therapy alone in the treatment of acne vulgaris, and has a time-effect correlation.摘要目的观察耳穴刺络放血加耳穴贴压治疗寻常性痤疮的临床疗效.方法将66例寻常性痤疮患者根据随机数字表分为观察组和对照组, 每组33例. 观察组采用耳穴刺络放血加耳穴贴压治疗, 对照组仅采用耳穴贴压治疗. 两组均每周治疗2次, 4周为1个疗程, 共治疗3个疗程. 分别于治疗前和治疗后记录患者皮损积分和皮肤病生活质量指数(DLQI)积分, 并据此进行疗效评定.结果试验过程中观察组和对照组均脱落3例. 3个疗程结束后, 观察组总有效率为96.7%; 对照组总有效率为76.7%, 差异有统计学意义(P<0.05). 组内比较显示, 两组患者皮损积分和DLQI积分均随治疗次数的增加而降低, 后一时间点积分均低于前一时间点(均P<0.05). 两组患者治疗1、2、3个疗程后的皮损积分和DLQI积分均与本组治疗前比较有统计学差异(均P<0.05). 组间比较显示, 治疗后每个时间点, 观察组皮损积分与DLQI积分均低于对照组, 组间差异均有统计学意义(均P<0.05).结论耳穴刺络放血加耳穴贴压治疗寻常性痤疮的临床疗效优于单独耳穴贴压治疗, 且存在时间-效应关系.