LAUSR

Objective To observe the effect of electroacupuncture plus drug anesthesia on pain and stress response in patients after radical surgery for stomach cancer. Methods A total of 60 patients were randomized into a control group and an observation group by the random number table, with 30 cases in each group. The control group was given conventional drug anesthesia. The observation group was given additional electroacupuncture intervention. Before anesthesia and 2 h, 12 h and 24 h after surgery, the visual analog scale (VAS) was scored, the heart rate, the mean arterial pressure, and the levels of serum β-endorphin (β-EP) and adrenocorticotrophic hormone (ACTH) were measured. Results Two hours, 12 h and 24 h after surgery, the VAS scores of both groups were higher than those before anesthesia (all P <0.05), and the VAS scores in the observation group were lower than those in the control group at the same time points (all P <0.05). Two hours, 12 h and 24 h after surgery, the heart rates and mean arterial pressures in the control group were significantly higher than those before anesthesia (all P <0.05), while there were no significant intra-group differences in the observation group (all P >0.05), and the indicators were lower than those in the control group at the same time points (all P <0.05). Two hours, 12 h and 24 h after surgery, the serum β-EP levels in the observation group were significantly higher than those before anesthesia (all P <0.05), and significantly higher than those in the control group at the same time points (all P <0.05). Two hours, 12 h and 24 h after surgery, the serum ACTH levels in the control group were significantly higher than those before anesthesia (all P <0.05), and were significantly higher than those in the observation group at the same time points (all P <0.05). Conclusion Electroacupuncture plus drug anesthesia can significantly relieve pain and stress response in patients after radical surgery for stomach cancer. 目的 观察电针加药物麻醉对胃癌根治术患者疼痛及应激反应的影响. 方法 将60例患者按照随机数表法分为对照组和观察组, 每组30例. 对照组予常规药物麻醉, 观察组在对照组药物麻醉基础上加电针干预. 于麻 醉前、 术后2 h、 术后12 h和术后24 h进行视觉模拟量表(VAS)评分, 测量心率和平均动脉压, 测定血清β-内啡肽(β-EP) 和促肾上腺皮质激素(ACTH)水平. 结果 术后2 h、 12 h及24 h, 两组的VAS评分均高于麻醉前(均 P <0.05), 观察组 VAS评分均低于同期对照组(均 P <0.05). 术后2 h、 12 h及24 h, 对照组心率和平均动脉压均明显高于本组麻醉前(均 P <0.05), 观察组心率和平均动脉压与麻醉前无显著差异(均 P >0.05), 且均低于同期对照组(均 P <0.05). 术后2 h、12 h及24 h, 观察组血清β-EP水平明显高于麻醉前(均 P <0.05), 且明显高于同期对照组(均 P <0.05). 术后2 h、 12 h 及24 h, 对照组血清ACTH水平显著高于麻醉前( P <0.05), 且明显高于同期观察组( P <0.05). 结论 电针加药物麻醉可明显缓解胃癌根治术患者的疼痛症状, 减轻应激反应.