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Heart Transplant Donor Selection Guidelines: Review and Recommendations

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The rate of heart transplants, while steadily increasing, is insufficient to meet the growing list of transplant candidates. Marginal donors expand the donor pool. However, criteria used to identify donors… Click to show full abstract

The rate of heart transplants, while steadily increasing, is insufficient to meet the growing list of transplant candidates. Marginal donors expand the donor pool. However, criteria used to identify donors greatly vary by institution. The International Society of Heart and Lung Transplant (ISHLT) heart transplant report of 2020 reinforced the importance of donor selection criteria on heart transplant outcomes. Existing literature challenges and reinforces the report’s findings. Newer methods, such as donation after circulatory death (DCD), also recontextualize existing donor selection criteria. Transplant prediction models from international databases are poor predictors of individual centers’ outcome. Further study is needed to understand associations among donor risk factors, and update the methods used for donor heart selection. In this review, we examine the current literature on extended donor criteria and recommend a model for donor selection.

Keywords: donor selection; transplant; heart transplant; heart

Journal Title: Current Cardiology Reports
Year Published: 2022

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