LAUSR

Primary lymphoma of the pancreas is an extraordinarily rare disease localized in the pancreas. It accounts for 0.1 to 4.9% of all pancreatic masses and less than 0.5% of all lymphoma cases [1, 2]. Most pancreatic solid tumors are adenocarcinomas (85–90%) and originate from the parenchyma; in contrast, pancreatic lymphomas usually have nodal origins. Extranodal lymphomas represent 30–40% of all lymphomas, and about half of these cases are in the gastrointestinal tract at the stomach or small intestine [2, 3]. About one-third of cases of non-Hodgkin’s lymphomas involve the pancreas secondarily through contiguous spread from peripancreatic lymph nodes [4]. In recent years, there has been a growing concern to distinguish primary pancreatic lymphoma because it is primarily treated through chemotherapy and has a better prognosis as compared to adenocarcinomas and other solid tumors of the pancreas [5]. Unlike adenocarcinomas, it is best to avoid surgery in PPL due to their excellent response to chemotherapy [5]. In this case report, we examine an elderly male who presented with a primary pancreatic lymphoma that was successfully treated with chemotherapy.