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Plasmacytic Differentiation in MALT Lymphoma: a Clue to Paraproteinemia—an Unusual Case of MALT Lymphoma of Small Intestine with IgA Heavy Chain Production and Kappa Light Chain Restriction

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Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) is an extranodal lymphoma composed of morphologically heterogeneous small B-cells, such as marginal zone cells, small lymphocytes, monocytoid cells, immunoblasts,… Click to show full abstract

Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) is an extranodal lymphoma composed of morphologically heterogeneous small B-cells, such as marginal zone cells, small lymphocytes, monocytoid cells, immunoblasts, and centroblast-like cells. Plasmacytic differentiation is frequently found in cutaneous MALT lymphomas and is a constant feature in thyroid MALT lymphomas. It is also described in gastric MALT lymphoma [1, 2]. Small intestinal MALT lymphoma is rare, and the degree of plasmacytic differentiation is unknown. We encountered a rare case of MALT lymphoma of the small intestine showing extensive plasma cell differentiation with IgA antibody production and kappa light chain restriction. Case report

Keywords: chain; malt; lymphoma small; plasmacytic differentiation; malt lymphoma

Journal Title: Journal of Gastrointestinal Cancer
Year Published: 2021

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