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Musashi1 (Msi1) is an RNA-binding protein that is involved in cell fate determination. Here, we report the 1H, 15N, and 13C resonance assignments of Msi1 second RNA-binding domain in free… Click to show full abstract
Musashi1 (Msi1) is an RNA-binding protein that is involved in cell fate determination. Here, we report the 1H, 15N, and 13C resonance assignments of Msi1 second RNA-binding domain in free form and in complex with RNA. The assignments can be utilized for NMR structure and dynamics analyses of the Msi1:RNA complex, and moreover, for chemical shift perturbation analyses to evaluate the binding of potential small molecule inhibitors against Msi1:RNA interaction.
Keywords:
binding domain;
form complex;
free form;
rna;
second rna;
rna binding
Journal Title: Biomolecular NMR Assignments
Year Published: 2017
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Journal Title: Biomolecular NMR Assignments
Year Published: 2017
Link to full text (if available)
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recommendations!