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Apolipoprotein E (ApoE) is one of the major lipid transporters in humans. It is also implicated in pathological conditions like Alzheimer's and cardiovascular diseases. The N-terminal domain of ApoE binds… Click to show full abstract
Apolipoprotein E (ApoE) is one of the major lipid transporters in humans. It is also implicated in pathological conditions like Alzheimer's and cardiovascular diseases. The N-terminal domain of ApoE binds low-density lipoprotein receptors (LDLR) while the C-terminal domain binds to the lipid. I report the backbone and aliphatic side-chain NMR chemical shifts of the N-terminal domain of two isoforms of ApoE, namely ApoE3 NTD (BMRB No. 51,122) and ApoE4 NTD (BMRB No. 51,123) at pH 3.5 (20 °C).
Keywords:
shift assignments;
chemical shift;
domain two;
terminal domain;
domain;
two isoforms
Journal Title: Biomolecular NMR assignments
Year Published: 2022
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Journal Title: Biomolecular NMR assignments
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!