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Homologous repair deficiency is a clinically relevant molecular aberration in prostate cancer. The goal of this short review is to summarize the study landscape of treatments targeting these aberrations through discussion… Click to show full abstract
Homologous repair deficiency is a clinically relevant molecular aberration in prostate cancer. The goal of this short review is to summarize the study landscape of treatments targeting these aberrations through discussion of the most relevant clinical trials. Due to its shortness, this review does not claim to be exhaustive and a major focus is being laid on PARP inhibitors in clinical development for prostate cancer.
Keywords:
parp inhibitors;
prostate cancer;
cancer;
homologous repair;
repair deficiencies
Journal Title: memo - Magazine of European Medical Oncology
Year Published: 2020
Link to full text (if available)
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Journal Title: memo - Magazine of European Medical Oncology
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!