LAUSR

Traditionally, Peacock feathers have been used for ornamental purposes, and as a curing agent against treacherous snakes’ venom (protease enzyme). We have evaluated peacock feathers as synergetic support for the synthesis of Ag and Au nanoparticles, and their bactericidal and urease enzyme inhibitory properties. We are the first to report the synthesis of peacock feathers extract (PFE) stabilized silver (AgNPs) and gold (AuNPs) nanoparticles, and their evaluation for antibacterial and urease enzyme inhibitory activities. The corresponding nanoparticles are characterized by different spectroscopic techniques such as UV–Vis Spectroscopy, Atomic Force Microscopy (AFM), and Transmission Electron Microscopy (TEM). UV–Vis spectra peaks at 395 nm and 511 nm confirmed the synthesis of AgNPs and AuNPs respectively. Further, the shape and size of nanoparticles are confirmed by AFM and TEM analysis, and their sizes are in the range of 4–20 nm for AgNPs and 7–25 nm AuNPs. Moreover, the stability of nanoparticles is investigated against various parameters such as temperature, acidity, alkalinity, and salinity. Bioactivities of PFE, AgNPs, and AuNPs examined and maximum inhibition efficacy reported against urease by AgNPs nanoparticles 99.7% with IC50, 28.5 ± 0.94 μg/mL and PFE 99.4% with IC50 58.5 ± 1.39 μg/mL, and the corresponding nanoparticles also found active against different bacterial strains.