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The Possibilities Given by First Trimester Prenatal Screening Data, Uterine Arteries Pulsation Index, and Regulatory Autoantibodies in Predicting Intrauterine Growth Restriction in Females

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A combined analysis of pregnancy-associated plasma protein-A (PAPP-A) values, human chorionic gonadotropin, and pulsation index of the uterine arteries was performed as part of a first trimester and serum content… Click to show full abstract

A combined analysis of pregnancy-associated plasma protein-A (PAPP-A) values, human chorionic gonadotropin, and pulsation index of the uterine arteries was performed as part of a first trimester and serum content of eight regulatory autoantibodies screening. It was found that including autoantibodies to insulin, PAPP-A, and collagen into the analysis significantly improved the sensitivity and specificity of the prognosis and could be employed to form an intrauterine growth restriction (IUGR) risk group.

Keywords: uterine arteries; growth restriction; regulatory autoantibodies; pulsation index; intrauterine growth; first trimester

Journal Title: BioNanoScience
Year Published: 2017

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