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Sebaceous Cell Carcinoma of the Lower Eyelid in an Elderly Male: a Rare Case Report and Review of Literature

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Sebaceous cell carcinoma (SCC) arises from the sebaceous gland and it is considered as one of the aggressive dermatological malignancy. It may have an ocular as well as extraocular origin… Click to show full abstract

Sebaceous cell carcinoma (SCC) arises from the sebaceous gland and it is considered as one of the aggressive dermatological malignancy. It may have an ocular as well as extraocular origin however, the most common site is the ocular region with the accountability of 34–59% cases [1]. The most common site of ocular origin is the upper eyelid due to the dense concentration of meibomian glands and involvement of the lower eyelid is a very rare presentation [2]. However simultaneous involvement of both eyelids has been found in about 1–6% of cases [3]. It is considered the third most common malignancy in the USA after basal cell carcinoma (BCC) followed by squamous cell carcinoma (SCC) which is contrary to Asian people in whom it is more common than BCC with accountability of around 28–60% of all ocular malignancies [4]. SCC is most commonly found in elderly patients with age range from 70 to 72 with no gender differentiation [5]. The origin of SCC is found in the meibomian gland, caruncle, gland of Zeis, and skin of the eyebrow [6]. There are other ocular pathologies including both benign and malignant entities which may mimic SCC. These are chalazion, BCC, squamous cell carcinoma, ocular pemphigoid, conjunctivitis, blepharitis, and leukoplakia. Thus, during evaluation of SCC, all these pathologies should be addressed first and then definitive management of SCC can be planned. We are reporting a case of an elderly male who presented to us with post excision status with positive margins who underwent re-wide excision (Fig. 1).

Keywords: cell carcinoma; lower eyelid; scc; sebaceous cell; cell

Journal Title: Indian Journal of Surgical Oncology
Year Published: 2021

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