LAUSR.org creates dashboard-style pages of related content for over 1.5 million academic articles. Sign Up to like articles & get recommendations!

A brief review of applications of antifreeze proteins in cryopreservation and metabolic genetic engineering

Photo from wikipedia

Antifreeze proteins (AFPs) confer the ability to survive at subzero temperatures and are found in many different organisms, including fish, plants, and insects. They prevent the formation of ice crystals… Click to show full abstract

Antifreeze proteins (AFPs) confer the ability to survive at subzero temperatures and are found in many different organisms, including fish, plants, and insects. They prevent the formation of ice crystals by non-colligative adsorption to the ice surface and are essential for the survival of organisms in cold environments. These proteins are also widely used for cryopreservation, food technology, and metabolic genetic engineering over a range of sources and recipient cell types. This review summarizes successful applications of AFPs in the cryopreservation of animals, insects, and plants, and discusses challenges encountered in cryopreservation. Applications in metabolic genetic engineering are also described, specifically with the overexpression of AFP genes derived from different organisms to provide freeze protection to sensitive crops seasonally exposed to subzero temperatures. This review will provide information about potential applications of AFPs in the cryopreservation of animals and plants as well as in plant metabolic genetic engineering in hopes of furthering the development of cold-tolerant organisms.

Keywords: insects; antifreeze proteins; metabolic genetic; cryopreservation; genetic engineering

Journal Title: 3 Biotech
Year Published: 2019

Link to full text (if available)


Share on Social Media:                               Sign Up to like & get
recommendations!

Related content

More Information              News              Social Media              Video              Recommended



                Click one of the above tabs to view related content.