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Abdominal manifestations of IgG4-related disease: a pictorial review

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In the last decade, autoimmune pancreatitis has become recognised as part of a wider spectrum of IgG4-related disease, typically associated with elevated serum IgG4 levels and demonstrating a response to… Click to show full abstract

In the last decade, autoimmune pancreatitis has become recognised as part of a wider spectrum of IgG4-related disease, typically associated with elevated serum IgG4 levels and demonstrating a response to corticosteroid therapy. Radiologically, there is imaging overlap with other benign and neoplastic conditions. This pictorial review discusses the intra-abdominal manifestations of this disease on cross-sectional imaging before and after steroid treatment and the main radiological features which help to distinguish it from other key differentials.Teaching Points• Autoimmune pancreatitis is part of a spectrum of IgG4-related disease.• Diagnosis is based on raised serum IgG4, clinical, radiological and histopathological findings.• Cross-sectional imaging can demonstrate the typical findings of abdominal IgG4-related disease.• Cross-sectional imaging can be used to monitor response to corticosteroid treatment.

Keywords: abdominal manifestations; igg4 related; related disease; pictorial review

Journal Title: Insights into Imaging
Year Published: 2018

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