LAUSR

Center for Applied Genomics at The Children’s Hospital of Philadelphia (CHOP) in collaboration with University Medical Center, Rotterdam performed a genome-wide association study (GWAS) on two discovery cohorts with DNA samples from 11,000 children. They found that an association between AOM and a site on chromosome 6 containing the gene FNDC1, and then replicated the finding in an independent pediatric cohort with data from 2000 children. The researchers said that although the gene’s function in humans has not been well studied, as per studies done in mouse FNDC1 codes for a protein with a role in inflammation.