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Extensive Juvenile Xanthogranuloma

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tinge) are located in any part of the body; mucosal lesions are rare. In rare cases, it can involve eye-resulting in blindness as a consequence of glaucoma and bleeding in… Click to show full abstract

tinge) are located in any part of the body; mucosal lesions are rare. In rare cases, it can involve eye-resulting in blindness as a consequence of glaucoma and bleeding in to the anterior chamber. Multinucleated giant cells (Touton cells) are observed on histopathology. They have a ring of nuclei around high lipid content cytoplasm. Immunohistochemical staining plays a key role in diagnosis; CD68 and vimentin are positive, whereas CD1a is usually negative.

Keywords: juvenile xanthogranuloma; extensive juvenile; histopathology

Journal Title: Indian Pediatrics
Year Published: 2018

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