Survival in childhood cancer has improved to approximately 80% in high-income countries (HIC) [1]. This success story is attributable to advances in diagnosis and risk stratification, and the protocolized administration… Click to show full abstract
Survival in childhood cancer has improved to approximately 80% in high-income countries (HIC) [1]. This success story is attributable to advances in diagnosis and risk stratification, and the protocolized administration of cytotoxic therapy [1,2]. However, the survival lags by 50% in low-income and low-and middle-income countries (LMIC) [1]. The road blocks faced by children with cancer in LMIC include resource constraints, a delayed presentation with advanced disease, treatment abandonment, malnutrition, and increased treatment-related toxicity. Treatment protocols that have been established and validated in HIC are not designed to address the challenges prevalent in LMICs [2]. Malignancy accounts for approximately 1% of deaths in children aged 5-14 years in India [3]. Novel Cost-effective strategies to treat children with cancer are of immense importance in LMICs such as India.
               
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