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Condition-controlled selective synthesis of hydroxyl(indolyl)- and bis(indolyl)barbiturates

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By combining the structural features of indole and barbituric acid, new hybrid molecules were designed and synthesized. Hydroxy(indolyl)barbiturates and bis(indolyl)barbiturates were selectively prepared via the reaction of indoles with alloxan… Click to show full abstract

By combining the structural features of indole and barbituric acid, new hybrid molecules were designed and synthesized. Hydroxy(indolyl)barbiturates and bis(indolyl)barbiturates were selectively prepared via the reaction of indoles with alloxan derivatives in various conditions.Graphical Abstract

Keywords: bis indolyl; indolyl barbiturates; selective synthesis; controlled selective; indolyl; condition controlled

Journal Title: Journal of the Iranian Chemical Society
Year Published: 2017

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