LAUSR

In this work, we fabricated a new renewable syringe carbon paste electrode (SCPE) equipped with a motor rotary cutting blade and used for voltammetric determination of dipyridamole (DIP) in aqueous solution, at room temperature. The cutter rotates by a small electrical motor and easily renews the surface of the carbon paste electrode by removing the spotty surface. Electrochemical performance of the constructed electrode was investigated with cyclic voltammetry (CV) and compared to some other previously reported works. The new sensor showed several advantages such as excellent repeatability, high stability, good sensitivity and easily surface renewable. The results indicated that the presence of methyltrioctyl ammonium chloride (MTOAC) could remarkably enhance the oxidation of DIP due to feasible electrical conductivity properties in a phosphate buffer solution. At optimum conditions for the new syringe CPE, the square wave voltammetry (SWV) was used to measure the concentration of DIP in a linear range of 0.08–30.0 µM and a detection limit of 0.02 µM was obtained after 100 s of accumulation time. The sensor was then tested for the simple, rapid and sensitive electrochemical determination of DIP in real samples such as pharmaceutical formulations.