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Two mixed-ligand coordination compounds: crystal structure and anti-liver cancer activity

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Two 3D mixed-ligand coordination compounds, [Cd(1,3-bdc)(bmip)]n[1, H21,3-bdc = 1,3-benzenedicarboxylic acid, bmip = 1,3-bis(2-methyl-1H-imidazol-1-yl)propane] and [Cd(5-mpc)(bmip)]n (2, H25-mpc = 5-methylisophthalic acid), have been successfully synthesized under hydrothermal conditions and characterized successfully… Click to show full abstract

Two 3D mixed-ligand coordination compounds, [Cd(1,3-bdc)(bmip)]n[1, H21,3-bdc = 1,3-benzenedicarboxylic acid, bmip = 1,3-bis(2-methyl-1H-imidazol-1-yl)propane] and [Cd(5-mpc)(bmip)]n (2, H25-mpc = 5-methylisophthalic acid), have been successfully synthesized under hydrothermal conditions and characterized successfully by single crystal X-ray analysis. In addition, in vitro anticancer activities of compounds 1 and 2 on three human liver cancer cells (PLC/PRF/5, BEL-7404 and MHCC97-L) were further determined.

Keywords: coordination compounds; two mixed; mixed ligand; liver cancer; ligand coordination

Journal Title: Journal of the Iranian Chemical Society
Year Published: 2018

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