LAUSR

Posterior reversible encephalopathy syndrome (PRES) is a well-known reversible clinicoradiologic entity for which typical MRI findings are vasogenic oedema of cortical and subcortical white matter within the parieto-occipital or posterior frontal lobes, with a variety of clinical manifestations, such as headache, seizures, altered mental status, and visual disturbance [1, 2]. An atypical imaging manifestation of PRES, called central-variant PRES, involves the brainstem or basal ganglia and possibly the periventricular white matter or thalamus, in which the cerebral cortical and subcortical white matter abnormalities are absent [3]. However, reversible involvement of bilateral corticospinal tracts is rarely reported. Herein, we report, to our knowledge, the first case of central-variant PRES with symmetrical bilateral corticospinal tracts involvement in brain MRI.