The present study investigates antimycotic potential of endophytic fungi towards economically relevant plant pathogenic organisms, viz. Rhizoctonia solani, Fusarium oxysporum, Sclerotinia sclerotiorum and Botrytis cinerea . Plant-derived by-products such as… Click to show full abstract
The present study investigates antimycotic potential of endophytic fungi towards economically relevant plant pathogenic organisms, viz. Rhizoctonia solani, Fusarium oxysporum, Sclerotinia sclerotiorum and Botrytis cinerea . Plant-derived by-products such as saponins and essential oils are considered as effective antifungal agents. Therefore, essential-oil-producing plants, viz. Ocimum sanctum and Mentha piperita , and saponin-producing plants, viz. Asparagus racemosus and Chlorophytum borivilianum , were selected as host plants. Bioactive secondary metabolites identified by GC-MS analysis, i.e. 6-pentyl-5,6-dihydro-2H-pyran-2-one and methyl hexadecanoic acid, demonstrated strong antimycotic activity towards F . oxysporum and S. sclerotiorum having IC 50 value of 0.662 ppm and 1.002 ppm, respectively. Sulphamethazine was recognised as potent antifungal metabolite in bioactive fraction of Acremonium sp. through UPLC-MS/MS dereplication.
               
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