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In this study, a dissipative particle dynamics mehtod was used to study the solubilization enhancing effect of platycodin towards 5 different drug components. Two factors were mainly considered, including the… Click to show full abstract
In this study, a dissipative particle dynamics mehtod was used to study the solubilization enhancing effect of platycodin towards 5 different drug components. Two factors were mainly considered, including the XlogP value of drug components and the sugar chain length of platycodin. As a result, it was found that there was an optimal drug XlogP value for the solubilization enhancing effect of platycodin, and it was different between the drug’s own XlogP value and the optimal drug XlogP value of platycodin that determines the solubilization enhancing effect.
Journal Title: Chemical Research in Chinese Universities
Year Published: 2019
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