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A series of highly functionalized 1,4-dihydropyridines was synthesized via one-pot multicomponent reactions of aromatic aldehyde, malononitrile and N-methyl-1-(methylthio)-2-nitroethenamine using Porcine pancreatic lipase(PPL) as catalyst in DMSO. This protocol is featured… Click to show full abstract
A series of highly functionalized 1,4-dihydropyridines was synthesized via one-pot multicomponent reactions of aromatic aldehyde, malononitrile and N-methyl-1-(methylthio)-2-nitroethenamine using Porcine pancreatic lipase(PPL) as catalyst in DMSO. This protocol is featured by mild reaction conditions, simple operation and environmental acceptability.
Keywords:
porcine pancreatic;
highly functionalized;
pot multicomponent;
using porcine;
functionalized dihydropyridines;
one pot
Journal Title: Chemical Research in Chinese Universities
Year Published: 2019
Link to full text (if available)
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Journal Title: Chemical Research in Chinese Universities
Year Published: 2019
Link to full text (if available)
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recommendations!