LAUSR.org creates dashboard-style pages of related content for over 1.5 million academic articles. Sign Up to like articles & get recommendations!

The thickening of flexor tendons pulleys: a useful ultrasonographical sign in the diagnosis of psoriatic arthritis

Photo by nate_dumlao from unsplash

PurposeTo investigate the frequency of thickening of pulleys for flexor tendons in patients with early arthritis in their hands, and to evaluate it as a predictive sign of PsA.MethodsA prospective… Click to show full abstract

PurposeTo investigate the frequency of thickening of pulleys for flexor tendons in patients with early arthritis in their hands, and to evaluate it as a predictive sign of PsA.MethodsA prospective observational study involving 228 consecutive patients presenting with recent onset of arthritis in their hands was conducted at rheumatology outpatient clinics in the Veneto region of Italy between October 2014 and September 2017. Diabetic patients were excluded because of the high frequency of trigger finger. The final diagnosis of the rheumatologist delivered after 12 months of follow-up, was considered as the gold standard for the analysis of diagnostic accuracy.ResultsTwenty-two patients were excluded from the study because of diabetes. A total of 86 patients with thickening of A1 pulleys in flexor tendons and 120 without were evaluated. Pulley thickness was significantly associated with a family history of psoriasis (18/86 vs 3/120, p ˂ 0.001) and diabetes (9/86 vs 4/120, p = 0.036), and with a personal history of cutaneous psoriasis (25/86 vs 10/120, p ˂ 0.001), psoriatic onychopathy (7/86 vs 2/120, p = 0.028), lower back pain (22/86 vs 11/120, p = 0.001), Dupuytren’s disease (7/86 vs 2/120 p = 0.028) and De Quervain tenosynovitis (4/86 vs 0/120, p = 0.028). In isolation, this sign had a good sensitivity rate (80%). The specificity rate for the disease was barely significative (71%), with an LR+ of 2.71 for PsA.ConclusionsThe thickening of the pulleys in the flexor tendons is an easy-to-detect sign with good sensitivity for the diagnosis of PsA. Its specificity and positive predictive value are not very high; however, if it is included in a complete classification process, sonographers should report it during hand evaluations of patients with arthritis.SommarioScopoStudiare la frequenza di ispessimento delle pulegge tendinee A1 (A1P) dei muscoli flessori delle dita in pazienti affetti da artrite della mano in fase precoce e valutarlo come un segno predittivo di Artrite Psoriasica (AP).MetodiUno studio prospettico osservazionale multicentrico su 228 pazienti ambulatoriali consecutivi che presentavano recente insorgenza di artrite alle mani tra ottobre 2014 e settembre 2017. I pazienti diabetici sono stati esclusi a causa dell’alta frequenza di dito a scatto. La diagnosi finale del Reumatologo Curante dopo un follow-up di 12 mesi è stata confrontata come Gold Standard.RisultatiUn totale di 86 pazienti con ispessimento delle A1P e 120 senza sono stati arruolati. L’ispessimento delle A1P era significativamente associato a storia familiare di psoriasi (18/86 vs 3/120, p ˂ 0.001) e di diabete (9/86 vs 4/120, p = 0.036), con storia personale di psoriasi cutanea (25/86 vs 10/120, p ˂ 0.001), di onicopatia psoriasica (7/86 vs 2/120, p = 0,028), di lombalgia (22/86 vs 11/120, p = 0,001), di malattia di Dupuytren (7/86 vs 2/120 p = 0,028) e di tenosinovite di De Quervain (4/86 vs 0/120, p = 0,028). Isolato, questo segno ha dimostrato una buona sensibilità (80%) per la diagnosi di AP; la specificità per AP era appena significativa (71%) con una LR+ di 2,71.ConclusioniL’ispessimento delle A1P è facile da individuare con una buona sensibilità per la diagnosi di AP. La specificità e il VPP non erano molto elevati. Tuttavia, lo studio ecografico delle pulegge tendinee dovrebbe essere incluso nel processo diagnostico di pazienti con artrite acrale all’esordio.

Keywords: arthritis; delle; sign; 120 001; 120 028; flexor tendons

Journal Title: Journal of Ultrasound
Year Published: 2018

Link to full text (if available)


Share on Social Media:                               Sign Up to like & get
recommendations!

Related content

More Information              News              Social Media              Video              Recommended



                Click one of the above tabs to view related content.