LAUSR

To identify an approach for contraception use in systemic lupus erythematosus (SLE), we take an in-depth look at the available contraceptive methods for female patients, their safety profile and possible drug interactions. Among the possible options, long-acting reversible contraceptives (LARCs) are considered the most effective option and should be considered in most cases. Combined hormonal contraceptives (CHCs) can also be used safely, except in case of active SLE or those at increased risk of thrombosis. Progestin-only contraceptives (POCs), on the other hand, are considered good alternatives for patients who have contraindications to CHCs. Contraception is a crucial issue in SLE given the potential pregnancy risks associated with active disease and teratogenic medications. It is important for both physician and patient to consider when pregnancy is not ideal due to health reasons or not desired; hence, proper education and counseling should be provided regarding the effects of SLE on pregnancy, as well as contraception. Several contraceptive options are available, and it is essential to understand the benefits and potential risks of each method to ensure reliable use of the most effective contraception for SLE patients.