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In vivo analysis of renal epithelial cells in zebrafish.

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The zebrafish kidney has been used effectively for studying kidney development, repair and disease. New gene editing capability makes it a more versatile in vivo vertebrate model system to investigate… Click to show full abstract

The zebrafish kidney has been used effectively for studying kidney development, repair and disease. New gene editing capability makes it a more versatile in vivo vertebrate model system to investigate renal epithelial cells in their native environment. In this chapter we focus on dissecting gene function in basic cellular biology of renal epithelial cells, including lumen formation and cell polarity, in intact zebrafish embryos.

Keywords: vivo analysis; biology; cells zebrafish; analysis renal; epithelial cells; renal epithelial

Journal Title: Methods in cell biology
Year Published: 2019

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