Infectious diseases, hormone abnormalities or fluctuations, some drugs and foods, and even neoplasias have been linked to EAC lesions. Annually recurring EAC may also involve seasonal environmental factors such as… Click to show full abstract
Infectious diseases, hormone abnormalities or fluctuations, some drugs and foods, and even neoplasias have been linked to EAC lesions. Annually recurring EAC may also involve seasonal environmental factors such as increased temperature or insect bites. A clear causal agent, however, cannot be identified in most cases (idiopathic EAC). With regard to treatment, topical and systemic corticosteroids may alleviate the pruritus, but they cannot halt the progress of the lesions, which may involve the entire chest, back or neck. Characteristic of EPSR and annually recurring EAC is the gradual and spontaneous regression of the lesions with the arrival of cooler seasons. Long-term follow-up has recorded recurrences in the first 2-5 years, with subsequent definitive resolution. Other publications, however, suggest a longer duration of the disease. Although EPSR has been described and subsequently reported in high-impact scientific journals, some authors question that it has sufficient clinical pathologic entity to be considered as an independent disease and they prefer to consider it as a peculiar variant of recurring figurate erythemas such as annually recurring EAC.
               
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