LAUSR

supervised regular use of a fluoride mouthrinse may result in large reductions in caries in the permanent teeth of children and adolescents, particularly in a school setting but also possibly in other settings such as at home, but with the caries-preventive effect being less clear. Critical summary assessment. This SR of 37 randomized or quasi-randomized controlled trials with high or unclear risk of bias reports moderate quality evidence that a fluoride mouthrinse may reduce caries increment in the permanent teeth of children and adolescents. Evidence quality rating. Limited.