RESULTS: Of 1,785 participants, 58 (3.3%) pregnancies resulted in stillbirth and 198 (11.4%) had a poor birth outcome. In multivariable analysis controlling for age, distance from hospital, referral status, receipt… Click to show full abstract
RESULTS: Of 1,785 participants, 58 (3.3%) pregnancies resulted in stillbirth and 198 (11.4%) had a poor birth outcome. In multivariable analysis controlling for age, distance from hospital, referral status, receipt of malaria prophylaxis, report of prior syphilis infection, and parity; attending 4 ANC visits was associated with significantly reduced odds of stillbirth (aOR 0.5, 95% CI 0.3-0.9, P1⁄40.02). Receipt of malaria prophylaxis at ANC was also independently associated with reduced odds of stillbirth (aOR 0.05, 95% CI 0.2-1.0, P1⁄40.04), but report of prior syphilis infection was not associated with stillbirth (aOR 1.0, 95% CI 0.2-1.5, P1⁄40.98). In a multivariable sensitivity analysis of risk factors associated with the composite poor birth outcome, attending 4 ANC visits remained associated with significantly reduced odds of poor birth outcomes when accounting for multiple potential confounders (aOR 0.66, 95% CI 0.4-0.96, P1⁄40.03). CONCLUSIONS: For this cohort of women in rural Uganda, attending 4 ANC visits was associated with reduced odds of stillbirth and poor birth outcomes, which may be related to receipt of antenatal infection screening, treatment, and prevention services.
               
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