LAUSR

165 Maternal celiac disease and long-term gastrointestinal morbidity of the offspring Gali Pariente, Tamar Wainstock, Eyal Sheiner Soroka University Medical Center, Ben-Gurion University of the Negev, Beer Sheva, Negev, Israel, Ben-Gurion University of the Negev, Beer Sheva, Negev, Israel OBJECTIVE: The development and availability of diagnosis made the prevalence of celiac disease to increase over the past 20 years. Celiac disease has been associated with adverse short-term perinatal outcomes such as low birthweight and preterm delivery. The aim of the present study was to determine whether being born to a mother with celiac disease increases the risk for long-term gastrointestinal morbidity of the offspring. STUDY DESIGN: A population-based cohort study, comparing longterm gastrointestinal morbidity of offspring of mothers with and without celiac disease was conducted. All singleton deliveries between the years 1991-2014 in a tertiary medical center were included. Cases of perinatal mortality, children with congenital malformations or chromosomal abnormalities and pregnancies without prenatal care were excluded from the study. The study groups were followed until 18 years of age for gastrointestinal