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(Figure 1). In SGA and FGR placentas, there is evidence of reduced telomerase activity and subsequent telomere shortening that could activate cell senescence and p53 (Figure 2). CONCLUSION: A comprehensive… Click to show full abstract
(Figure 1). In SGA and FGR placentas, there is evidence of reduced telomerase activity and subsequent telomere shortening that could activate cell senescence and p53 (Figure 2). CONCLUSION: A comprehensive assessment demonstrated accelerated placental aging in both clinical forms of late-onset fetal smallness, supporting a common pathophysiology and challenging the concept of SGA being ‘constitutionally small’.
Keywords:
remodeling associated;
preeclampsia fetal;
associated preeclampsia;
cardiac remodeling;
fetal growth;
fetal cardiac
Journal Title: American Journal of Obstetrics and Gynecology
Year Published: 2019
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Journal Title: American Journal of Obstetrics and Gynecology
Year Published: 2019
Link to full text (if available)
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recommendations!