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Variation in outcome reporting in studies on Vasa Previa: A Systematic Review: 332

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women. This study evaluated maternal and fetal responses to individually prescribed moderate-intensity exercise in pregnant women with chronic HTN. STUDY DESIGN: This prospective study evaluated maternal (blood pressure, heart rate,… Click to show full abstract

women. This study evaluated maternal and fetal responses to individually prescribed moderate-intensity exercise in pregnant women with chronic HTN. STUDY DESIGN: This prospective study evaluated maternal (blood pressure, heart rate, uterine artery Doppler velocimetry) and fetal (heart tracing, umbilical artery Dopplers, biophysical profile (BPP)) responses to 30 minutes of moderate-intensity (40-59% of heart rate reserve) exercise in pregnant women with chronic HTN. All were on antihypertensive medications and had no other medical comorbidities, known fetal abnormalities, or exercise contraindications. Testing occurred between 28-34 weeks. After peak exercise testing, individualized exercise prescriptions were developed. Women returned to perform a 30-minute treadmill exercise session at a heart rate within their target range. Blood pressures were measured every 5 minutes during exercise. Ultrasound before and immediately after exercise included umbilical and uterine artery Doppler velocimetry. BPPs and fetal heart tracings were recorded after exercise. Sample size calculations indicated n1⁄410 was sufficient to detect differences in uterine artery pulsatility index from the 50 to 90percentile. Paired t-tests and Wilcoxon matched-pairs signed-ranks tests (if not normally distributed) were utilized to evaluate pre-post differences (STATA 15.1). RESULTS: Ten women completed the study. Mean age was 33 4 years, BMI was 31.26 6.5 . See Table for test data. Variables were normally distributed, except for S/D ratios. Uterine and umbilical artery Doppler indices (Table) did not change with exercise. Blood pressures were mildly elevated during exercise (see Figure, means SD). BPPs and fetal heart rate tracings were reassuring after exercise. CONCLUSION: Pregnant women with chronic hypertension tolerated moderate-intensity exercise with no adverse changes in uterine artery Doppler measures, a reflection of uterine blood flow, or fetal well-being measures. Prescribed moderate exercise did not induce extremes of maternal blood pressure.

Keywords: heart; uterine artery; blood; exercise; heart rate

Journal Title: American Journal of Obstetrics and Gynecology
Year Published: 2019

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